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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are often characterized by a focus on the practical aspects of study design, such as recruitment and consent as well as adherence to the use of commonly available equipment.

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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which employed a variety of investigators and 프라그마틱 슬롯 추천 had participants from different geographic areas. This type of heterogeneity is essential for practical trials to be valid and reduces bias in the results. However excessive heterogeneity could cause issues with the design of the trial.

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Mobile compatibility

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Pragmatic Play offers not only mobile-friendly slot machines, but also tables games and live casinos. Pragmatic Play is licensed and regulated by a variety of regulatory bodies that include the Malta Gaming Authority and UK Gambling Commission. The company's games are protected by high-end encryption and its security staff is on hand to help players with any issues.

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Legality

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The goal of pragmatic trials is to mimic real-life scenarios and gain maximum credibility externally. They are typically requested by practitioners and policymakers in order to inform their decisions. They also provide a useful method to determine the cause-effect relationship between an intervention and its results. They should, however, not, be used to replace the need for explanation studies.

The pragmatism idea is controversial and there are doubts regarding whether pragmatic trials could be used to replace explanation tests or if they should be an addition to them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which confirm a physiological or clinical hypothesis, and pragmatic trials that inform the practice and 프라그마틱 슬롯 추천 policy decisions. They also suggested a framework for pragmatic trials, which they called PRECIS.2 This tool was designed to define the features of a pragmatic trial, including the recruitment process, the design and implementation of the intervention, and follow-up.

There is an encouraging trend in the number of pragmatic trials that have been published. A recent Medline search using the terms pragmatic and naturalistic, restricted to randomized controlled trials (RCTs) resulted in 34 articles, which are shown in red in Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatism. It is important to note, however, that the majority of studies were conducted in primary-care settings.