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Pragmatic trials are studies designed to provide information for real-world clinical practice. They are usually characterized by a focus on the practical aspects of study design, such as recruitment and consent as well as adherence to the use of routinely available equipment.

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Pragmatic is a software development company that provides a variety of casino games on online gambling platforms. Pragmatic's iGaming software is used by top operators as well as casinos that are located in the land. The company offers front-end tools for design, analysis, promotions, marketing, payment systems, security, customer service and bug reporting. Additionally, the company offers its users a safe environment with high-quality graphics as well as gaming.

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A practical trial that employs various investigators and participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity is essential for practical trials to be valid and also helps to reduce the chance of bias in the results. However too much heterogeneity could lead to issues with the design of the trial.

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Pragmatic Play offers not only mobile-friendly slot machines but also tables games and live casinos. Pragmatic Play is licensed and regulated by a variety of governing bodies, including the Malta Gaming Authority and UK Gambling Commission. The games of the company are secured by top-of-the-line encryption, and its security team is on hand to help players with any issues.

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Legality

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The aim of pragmatic trials is to mimic real-life scenarios and gain maximum validity externally. They are usually commissioned by policy makers and practitioners to aid in their decision-making. They can also be used to assess the causal relationship between an intervention with its outcomes. However, they shouldn't be used to substitute for explanation trials.

The pragmatism idea is controversial and there are questions about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 made the distinction between explanation studies, which confirm the validity of a physiological or clinical hypothesis, as well as pragmatic trials, which inform the decision-making process for policy and practice. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the traits of a pragmatic study that includes recruitment, design, implementation of the intervention, and 프라그마틱 슬롯체험 follow-up.

The number of pragmatic trials is increasing. A recent Medline search using the terms naturalistic and pragmatic, which was limited to controlled trials randomized to control (RCTs) resulted in 34 articles, which are shown in red in Figure 2. This is a sign that the health sciences community is becoming more acquaint to the subject of pragmatics. It is important to remember that the majority were conducted in primary-care settings.