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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are often described as a focus on the practical aspects of study design, including recruitment and consent, adherence and the use of standard equipment.
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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which used a variety of investigators and had participants from different geographical regions. This kind of heterogeneity is necessary for pragmatic trials to be able to prove their validity and helps reduce bias in the results. A high degree of heterogeneity, however could cause issues with the design of the trial.
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Pragmatic trials aim to mimic real-life settings and achieve maximum external validity. They are usually requested by practitioners and policy makers to aid in their decision-making. They can also be used to assess the cause-effect relationship of an intervention with its outcomes. However, they shouldn't be used to substitute for 프라그마틱 슬롯 무료 the use of explanation studies.
The pragmatism concept is controversial and there are questions about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which prove the clinical or physiological hypothesis and 프라그마틱 슬롯 사이트 pragmatic trials, which guide policy and practice decisions. They also suggested a framework for pragmatic trials, called PRECIS.2 This tool was designed to define the features of a pragmatic study that include the recruitment process, the design and delivery of the intervention, as well as follow-up.
The number of pragmatic trials is growing. A recent Medline search using the keywords pragmatic and naturalistic, restricted to controlled trials randomized to control (RCTs), 프라그마틱 슬롯체험 무료 슬롯 - please click the next website page - yielded 34 articles, which are shown in red in Figure 2. This is an indication that the health sciences community is becoming more acquaint to the issue of pragmatic thinking. It is important to note, however, that the majority of these studies were conducted in primary-care settings.