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Studies designed to provide insight into clinical practice in the real world are called pragmatic trials. They are typically described as a focus on the practical aspects of designing a study which include the recruitment and consent process, as well as adherence and the use routinely available equipment.
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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which utilized a variety of investigators and had participants from various geographical areas. This type of heterogeneity, that is crucial for pragmatic trials to be reliable and lessen the chance of bias, 무료슬롯 프라그마틱 is also necessary. However, too much heterogeneity could cause issues with the design of the trial.
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The goal of pragmatic trials is to replicate real-life scenarios and to achieve maximum credibility externally. They are typically requested by practitioners and policymakers to help inform their decisions. They can also be used to determine the cause-effect relationship of an intervention and its results. However, they should not be used to replace the need for explanation studies.
The pragmatism concept is controversial, and there are questions about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 suggested the distinction between explanation studies, which support the validity of a physiological or clinical hypothesis, 프라그마틱 슬롯 팁 and pragmatic trials that aid in the practice and policy decision-making. They also suggested a framework known as PRECIS for pragmatic trials.2 This tool tried to define the characteristics of a practical study, including recruitment, design, implementation of the intervention and follow-up.
There is an encouraging trend in the number of pragmatic trials that are published. A recent Medline query using the keywords pragmatic and 프라그마틱 슬롯 사이트 naturalistic, which was restricted to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This is an indication that the health science community is becoming more sensitive to the subject of pragmatics. It is important to keep in mind, however, that the majority of studies were conducted in primary care settings.