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Pragmatic trials are studies designed to inform the practice of clinical trials in real life. They are typically described as focusing on practical aspects of study design, including the recruitment and consent process, as well as adherence and the use routinely available equipment.
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Pragmatic, a software company, offers a variety of casino games for online gambling platforms. Its iGaming software is used by leading operators as well as land-based casinos. The company offers front-end design tools, analysis, marketing, promotions, payment systems, security, customer service and bug reporting. The company also provides an environment that is safe and secure with high-quality graphics, games and security.
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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which utilized various investigators and had participants from different geographic areas. This type of heterogeneity is necessary for pragmatic trials to be able to prove their validity, and it also reduces bias in the results. However, too much heterogeneity could cause issues with the design of the trial.
Pragmatic Play is also a major player on the live casino market, offering an extensive selection of classic table games such as Blackjack and Roulette in various versions. The live studios of the company in Romania and Malta offer customers an authentic experience in gambling as well as a broad selection of virtual betting options. The company also has several game shows that make online gambling more enjoyable and engaging. Some of these shows are broadcast live, while others are hosted by famous personalities from the industry.
Mobile compatibility
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Legality
Pragmatic Play is known for its top-quality games and also for providing an outstanding user experience. Its software is designed to work with mobile devices and supports various languages. Despite its infancy it has established itself as a premier casino gaming platform. The latest releases include Wolves 5 reel video slot with a healthful RTP and impressive graphics. Other notable titles include Wolf Gold and Chilli Heat.
Pragmatic trials are designed to replicate real-world situations and have the highest external validity. Usually, they are requested by practitioners and policymakers to guide their decisions. They can be used to determine the causal relationship between an intervention and its effects. They should, however, not, be used to replace explanatory studies.
The pragmatism idea is controversial, and there are questions regarding whether pragmatic trials could replace explanatory tests or if they should serve as an alternative to them. Schwartz and Lellouch1 made a distinction between explanatory studies, which prove a physiological hypothesis or clinical hypothesis, as well as pragmatic trials that aid in the decision-making process for policy and practice. They also proposed an approach to pragmatic trials, dubbed PRECIS.2 This tool attempted to define the characteristics of a pragmatic study, including the recruitment process, the design and implementation of the intervention, and follow-up.
The number of pragmatic trials is increasing. A recent Medline search using the keywords naturalistic and pragmatic, limited to controlled trials randomized to control (RCTs), yielded 34 articles, as shown in red in Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatic thinking. However, it is important to keep in mind that the majority of these studies were conducted in primary care settings.