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Trials designed to inform clinical practice in the real world are referred to as pragmatic trials. They are typically described by their focus on practical aspects of designing a study that include the recruitment and consent process, as well as adherence and the use of routinely available equipment.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which used various investigators and included participants from various geographical areas. This type of heterogeneity, which is vital for pragmatic trials to be reliable and to reduce bias in the results, 프라그마틱 슬롯 무료체험 is also necessary. However, too much heterogeneity can lead to issues with the design of the trial.

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The purpose of pragmatic trials is to mimic real-life situations and achieve the highest level of validity externally. They are typically commissioned by practitioners and policy makers to guide their decision-making. They can also be used to determine the causal relationship between an intervention and 무료슬롯 프라그마틱 its effects. However, they should not, be used to replace explanatory studies.

The pragmatism idea is controversial, and there are questions about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which prove the validity of a clinical or physiological hypothesis and pragmatic trials, which guide the policy and practice of. They also suggested an approach to pragmatic trials, called PRECIS.2 This tool sought to define the characteristics of a pragmatic trial which includes recruitment, design and delivery of the intervention, as well as follow-up.

There is a positive trend in the number of pragmatic trials that have been published. A recent Medline search using the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. These are shown in red on Figure 2. This is a sign that the health science community is becoming more sensitive to the issue of pragmatism. It is important to remember that the majority of studies were conducted in primary-care settings.