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Clinical trials that are designed to help inform practice in the real world are called pragmatic trials. They are typically described as focusing on practical aspects of study design, including recruitment and consent, adherence and 프라그마틱 슈가러쉬 the use of routinely available equipment.

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A pragmatic study that involves a variety investigators and includes participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is essential for 프라그마틱 플레이 practical trials to be valid and helps reduce the chance of bias in the results. A high degree of heterogeneity, however can result in problems with the trial design.

Pragmatic Play Pragmatic Play, one of the biggest players on the live casino market, provides various classic table games, including Blackjack and Roulette. The live studios of Pragmatic Play's offices in Romania and Malta provide customers with an authentic experience in gambling as well as a broad range of virtual betting options. The company also has created several interactive game shows to make online gambling enjoyable. Some of these shows are telecast live and some include famous people from the industry.

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Pragmatic trials aim to mimic real-life situations and attain maximum external validity. Usually, they are ordered by policymakers and practitioners to help inform their decisions. They also provide a useful method of determining the causal relationship between an intervention and its outcomes. They should, however, not, be used to replace the need for explanation studies.

The concept of pragmatism is controversial and there are concerns about whether pragmatic trials can replace tests for explanations or if they are an addition to them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which validate the clinical or physiological hypothesis and pragmatic trials, which guide policy and practice decisions. They also proposed an approach to pragmatic trials, called PRECIS.2 This tool sought to define the elements of a practical trial which includes the recruitment process, the design and delivery of the intervention, and the follow-up.

There is a growing trend in the number of pragmatic trials published. A recent Medline query that used the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs) returned 34 articles. These are shown in red on Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatic thinking. However, it is important to note that the majority of these trials were conducted in primary care settings.